Methods of Treating or Preventing Amyotrophic Lateral Sclerosis
Application
US20260077060A1
Kind: A1
Mar 19, 2026
Assignee
Rowan University
Inventors
Jeremy Francis, Paola Leone
Abstract
This disclosure provides methods for treating, ameliorating, or reversing at least one symptom of amyotrophic lateral sclerosis (ALS) in a subject by increasing the amount of neuronal aspartate in spinal cord through administration of a therapeutically effective amount of a composition comprising a nucleic acid encoding ASPA or a functional fragment thereof.
CPC Classifications
A61K 48/005
C12N 15/86
C12N 2750/14143
C12N 2750/14171
C12Y 305/01015
Filing Date
2025-11-21
Application No.
19396542