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COMBINATION THERAPY EMPLOYING A PD1-LAG3 BISPECIFIC ANTIBODY AND AN HLA-G T CELL BISPECIFIC ANTIBODY

Application US20260077044A1 Kind: A1 Mar 19, 2026

Assignee

Hoffmann-La Roche Inc.

Inventors

Meher MAJETY, Carina HAGE, Laura CODARRI DEAK, Valeria Gonzalez NICOLINI

Abstract

The invention relates to combination therapies employing an anti-PD1/anti-LAG3 bispecific antibody and an HLA-G T cell-activating bispecific antibody, the use of these combination therapies for the treatment of cancer and methods of using the combination therapies.

CPC Classifications

A61K 39/39558 A61P 35/00 A61K 2039/507

Filing Date

2025-08-26

Application No.

19310373