COMBINATION THERAPY

Abstract

The invention relates to methods of treating colorectal cancer in a subject in need thereof. The methods comprising co-administering to the subject: a) a DKK1 antibody, or antigen binding-fragment thereof; b) a VEGF or VEGFR inhibitor; and c) optionally one or more chemotherapeutic agents or a pharmaceutically acceptable salt of any of the foregoing, in an effective amount. The present invention also provides a pharmaceutical composition and a kit comprising a combination of a DKK1 antibody, and a VEGF or VEGFR inhibitor and optionally one or more chemotherapeutic agents.

CPC Classifications