NUCLEIC ACIDS ENCODING HUMAN ENDOGENOUS RETROVIRUS K (HERV-K) ENVELOPE PROTEINS CONTAINING MODIFIED IMMUNOSUPPRESSIVE DOMAINS (ISD) AND USES THEREOF
Application
US20260077031A1
Kind: A1
Mar 19, 2026
Assignee
INPROTHER APS
Inventors
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract
A vaccine for use in the prophylaxis and/or treatment of a disease The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
CPC Classifications
A61K 39/21
A61K 39/235
A61P 35/00
A61P 35/04
C07K 14/005
C12N 7/00
C12N 15/86
A61K 2039/525
A61K 2039/5258
A61K 2039/545
A61K 2039/585
C12N 2710/10043
C12N 2740/10022
C12N 2740/10023
C12N 2740/10034
C12N 2740/10071
Filing Date
2025-07-11
Application No.
19266325