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COMPLEX WITH STROKE THERAPEUTIC CHARACTERISTIC, AND PREPARATION METHOD AND USE THEREOF

Application US20260077010A1 Kind: A1 Mar 19, 2026

Assignee

Beijing Technology and Business University

Inventors

Hongzhi Liu, Xuchun Zhu, Shanyue Guan, Bingyu Chen, Chao Yan, Tong Meng, Mengfan Li

Abstract

The present invention discloses a complex with a stroke therapeutic characteristic, and a preparation method and use thereof. The complex is a complex of a yeast peptide and hydroxytyrosol. The yeast peptide is a yeast peptide with a molecular weight less than 3 kDa produced by papain enzymolysis of yeast protein. The pH during enzymatic hydrolysis is 6.8-7.2, the enzymatic hydrolysis time is 3.8-6.2 h, the enzymatic hydrolysis temperature is 48-58° C., and the ratio of the papain to the yeast protein in the enzymatic hydrolysis system is 8,800-9,200 U/g. The complex is used for manufacture of a drug for treating ischemic stroke. The present invention offers an efficient, safe, and cost-effective complex with a stroke therapeutic characteristic, featuring broad application prospects, and significant technical advantages, and the complex has a simple preparation method and low production cost.

CPC Classifications

A61K 38/01 A61K 31/05 A61P 9/10 C12N 1/16 C12N 9/63 C12P 21/06 C12Y 304/22002

Filing Date

2025-01-16

Application No.

19023413