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PRESERVATION OF PANCREATIC ISLET GRAFTS IN THE EXTRAHEPATIC SPACE

Application US20260076999A1 Kind: A1 Mar 19, 2026

Inventors

Casey Ward, Qizhi Tang, Peter Stock, Gaetano Faleo, Gopika Nair, Matthias Hebrok, Wenhan Chang, Thuy Vo, Jeffrey A. Bluestone, Eleonora De Klerk

Abstract

Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.

CPC Classifications

A61K 35/55 A61K 9/0019 A61K 9/0024 A61K 35/39 A61P 3/10 C12N 5/0617 C12N 5/0676 A61K 2300/00 C12N 2506/02 C12N 2506/078

Filing Date

2025-11-20

Application No.

19395694