TREATMENT FOR HEART FAILURE WITH PRESERVED EJECTION FRACTION WITH GUANETHIDINE AND GUANADREL
Application
US20260076976A1
Kind: A1
Mar 19, 2026
Inventors
Mathew MAURER, Marc GRODMAN
Abstract
The present invention is directed to a method of treating a patient diagnosed with or suffering from heart failure with preserved ejection fraction (HFpEF) by administering an effective amount of a peripherally-acting antihypertensive agent that reduces excessive venoconstriction (such as guanethidine, guanadrel, or a pharmaceutically acceptable salt thereof), alone or in combination with other agents.
CPC Classifications
A61K 31/5545
A61K 31/36
A61K 45/06
A61P 9/04
Filing Date
2025-08-15
Application No.
19301748