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AZA-QUINOLINE COMPOUNDS AND USES THEREOF

Application US20260076968A1 Kind: A1 Mar 19, 2026

Inventors

Ling LI, Xuan DAI, Michael DORE, Xiang-Ju Justin GU, Kun Chin LIU, Sing Yeung Frankie MAK, Yuan MI, Counde OYANG, Julien PAPILLON, Wei (Vicky) QI, Xiaoxia YAN, Zhengtian YU, Ji Yue (Jeff) ZHANG, Kehao ZHAO

Abstract

The invention disclosed herein relates to a method for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination EZH2 and PRC2, comprising administering to a subject in need thereof a therapeutically effective amount of the compound of Formula (I), or a stereoisomer, enantiomer, enantiomeric mixture or a pharmaceutically acceptable salt thereof;

CPC Classifications

A61K 31/506 A61K 31/5377 A61K 31/541 A61K 45/06 A61P 35/00 C07D 471/04

Filing Date

2025-11-21

Application No.

19396743