← USPTO Patent Applications

METAP2 INHIBITORS AND METHODS OF TREATING OBESITY

Application US20260076960A1 Kind: A1 Mar 19, 2026

Inventors

James SHANAHAN, John S. PETERSEN

Abstract

The present invention relates to modified or polymer conjugated MetAP2 inhibitors. The present invention also relates to methods of preventing, inducing, causing or increasing weight loss, treating obesity and/or treating metabolic syndrome utilizing the modified or polymer conjugated MetAP2 inhibitors. The present invention also relates to methods of improving insulin sensitivity and glycemic control, reducing insulin levels and/or improving leptin sensitivity utilizing the modified or polymer conjugated MetAP2 inhibitors.

CPC Classifications

A61K 31/485 A61K 31/336 A61K 31/77 A61K 47/542 A61K 47/58 A61K 47/65 A61P 3/04 A61P 3/08 A61P 3/10 A61P 5/50

Filing Date

2025-04-21

Application No.

19184440