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METHODS OF TREATING FABRY DISEASE IN PATIENTS HAVING RENAL IMPAIRMENT

Application US20260076951A1 Kind: A1 Mar 19, 2026

Assignee

Amicus Therapeutics, Inc.

Inventors

Franklin Johnson

Abstract

Provided are methods of treating Fabry disease in a patient having severe renal impairment. A method for the treatment of Fabry disease in a patient having severe renal impairment, including administering to the patient about 50 mg to about 200 mg free base equivalent (FBE) of migalastat or salt thereof at a frequency of less than once every week. A method for the treatment of Fabry disease in a patient having severe renal impairment, including administering to the patient about 50 mg to about 100 mg free base equivalent of migalastat or salt thereof at a frequency of between about once every three days and about once every two weeks.

CPC Classifications

A61K 31/445 A61P 13/12

Filing Date

2025-09-19

Application No.

19333835