AGENTS THAT TARGET TELOMERASE REVERSE TRANSCRIPTASE (TERT) FOR TREATING CANCER AND SENSITIZING CANCER CELLS TO GENOTOXIC THERAPY
Application
US20260076947A1
Kind: A1
Mar 19, 2026
Inventors
Karl A. Scheidt, Stephen J. Kron, Yue Liu
Abstract
Disclosed herein are agents that target telomerase reverse transcriptase (TERT) for treating cancer and sensitizing cancer cells to genotoxic therapy. The methods include inhibiting induction of an immunosuppressive factor in a subject in need thereof, the method comprising administering an inhibitor of TERT to the subject.
CPC Classifications
A61K 31/4192
A61K 45/06
A61P 37/06
Filing Date
2025-09-16
Application No.
19330600