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COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH

Application US20260076944A1 Kind: A1 Mar 19, 2026

Inventors

Elaine Y. Hsiao, Elena Coley-O'Rourke

Abstract

Disclosed herein are methods for promoting healthy neural development in a fetus, which include administering to a maternal subject gestating the fetus a composition. Compositions can include 3-indole sulfate, phenylacetylglycine, imidazole propionate, alpha-hydroxyisocaproate, 2-hydroxy-3-methylvalerate, alpha-hydroxyisovalerate, 1-methylhistamine, beta-hydroxyisovalerate, 2R, 3R-dihydroxybutyrate, or N-acetylleucine, or a combination thereof. Compositions can also include acetate, propionate, or butyrate, or a combination thereof. Also disclosed are methods for conditioning a female subject for bringing about offspring with healthy neural development.

CPC Classifications

A61K 31/417 A61K 31/191 A61K 31/198 A61K 31/404 A61K 31/4172 A61P 25/00

Filing Date

2025-09-17

Application No.

19331331