INDOLINONE COMPOUNDS AND USES THEREOF
Application
US20260076941A1
Kind: A1
Mar 19, 2026
Inventors
Jean-Michel Vernier
Abstract
Indolinone derivative compounds that act as EWS-PLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
CPC Classifications
A61K 31/404
A61K 31/4155
A61K 31/4439
A61K 31/5377
C07D 209/34
C07D 209/38
C07D 401/06
C07D 401/10
C07D 403/10
Filing Date
2025-09-22
Application No.
19335663