FORMULATIONS OF ANTI-INTERLEUKIN 1 RECEPTOR 1 ANTIBODIES
Application
US20260076903A1
Kind: A1
Mar 19, 2026
Inventors
Ajit D'Souza, Jianwen XU
Abstract
The present invention provides, among other things, stable formulations comprising an anti-Interleukin 1 Receptor 1 (IL1R1) antibody at a concentration of between than 50-200 mg/ml, wherein the formulation comprises less than 130 mM arginine and a pH of 4.4-6.5, wherein the amount of HMW species in the formulation increases less than 2% upon storage at 25° C. for at least 4 weeks.
CPC Classifications
A61K 9/08
A61K 47/12
A61K 47/22
A61K 47/26
C07K 16/2866
A61K 2039/545
C07K 2317/52
C07K 2317/565
Filing Date
2025-11-19
Application No.
19394710