LIPID COMPLEX

Publication EP4711463A1 Kind: A1 Mar 18, 2026

Applicants

Eisai R&D Management Co., Ltd., National University Corporation Kumamoto University

Inventors

SUZUKI, Yuta, KUBARA, Kenji, MIYAZAKI, Takayuki, MATSUOKA, Masao, YASUNAGA, Jun-ichirou

Abstract

[Problem] A composition and a method that can be used to induce an immune response to HTLV-1 are required. [Solution] A lipid complex comprising at least one nucleic acid selected from: a nucleic acid comprising a polynucleotide that encodes an immunogenic fragment of human T-cell leukemia virus 1 (HTLV-1) antigenic Gag protein; a nucleic acid comprising a polynucleotide that encodes an immunogenic fragment of HTLV-1 antigenic Tax protein; and a nucleic acid comprising a polynucleotide that encodes an immunogenic fragment of HTLV-1 antigenic HBZ protein; wherein the at least one nucleic acid is encapsulated in a lipid.

IPC Classifications

C12N 15/48 20060101AFI20241122BHEP A61K 9/14 20060101ALI20241122BHEP A61K 31/7088 20060101ALI20241122BHEP A61K 47/22 20060101ALI20241122BHEP A61K 47/24 20060101ALI20241122BHEP A61K 47/28 20060101ALI20241122BHEP A61K 47/34 20170101ALI20241122BHEP A61P 37/04 20060101ALI20241122BHEP C07K 14/15 20060101ALI20241122BHEP C12N 15/88 20060101ALI20241122BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →