PHENYLALANINE LYASE MUTANT, AND CONJUGATE THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Publication
EP4711453A1
Kind: A1
Mar 18, 2026
Applicants
Peg-Bio Biopharm Co., Ltd. (Chongqing)
Inventors
FAN, Kai, FU, Zhicheng, TANG, Guanghui, WU, Kuncan, ZENG, Xin, LUAN, Qiuyang, LIU, Riyong, CHEN, Qing
Abstract
Provided is a phenylalanine lyase mutant. Compared with the amino acid sequence of phenylalanine lyase, the phenylalanine lyase mutant has a mutation at at least one of the following sites: site 72, site 240, site 467 and site 544.
IPC Classifications
C12N 9/88 20060101AFI20241115BHEP
C12N 9/96 20060101ALI20241115BHEP
A61K 38/43 20060101ALI20241115BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR