← EPO Patent Bulletin

CAMPTOTHECIN DERIVATIVE, LINKER, LIGAND-DRUG CONJUGATE AND MEDICAL USE THEREOF

Publication EP4711371A1 Kind: A1 Mar 18, 2026

Applicants

Gan &Amp Lee Pharmaceuticals Co., Ltd.

Inventors

SUN, Yingjie, CUI, Menghan, JIAO, Jiao, WANG, Jiaxing, CHE, Liming, ZHANG, Guofu, CHEN, Wen

Abstract

Disclosed in the present invention are a new camptothecin derivative, a linker, a ligand-drug conjugate, and a pharmaceutical composition thereof containing the camptothecin derivative or the conjugate, and the corresponding medical use.

IPC Classifications

C07D 491/22 20060101AFI20241115BHEP A61K 31/4745 20060101ALI20241115BHEP A61P 35/00 20060101ALI20241115BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR