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A PROCESS FOR PREPARING 4-METHYL-2-PROPAN-2-YL-PYRIDINE-3-CARBONITRILE

Publication EP4711357A2 Kind: A2 Mar 18, 2026

Applicants

AMGEN, INC.

Inventors

SMITH, Austin Gerald, KAVURU, Padmini, DORNAN, Peter, DAI, Xijie

Abstract

Provided herein are processes for preparing Compound A or a salt thereof, comprising admixing Compound B or a salt thereof and crotonaldehyde in the presence of an acid catalyst and a solvent to form Compound A

IPC Classifications

C07D 213/85 20060101AFI20230915BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR