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DECREASING THE INTRINSICALLY DISORDERED PROTEIN ALPHA-SYNUCLEIN'S LEVELS BY TARGETING ITS STRUCTURED MRNA WITH A RIBONUCLEASE TARGETING CHIMERA

Publication EP4709715A1 Kind: A1 Mar 18, 2026

Applicants

University of Florida Research Foundation, Incorporated

Inventors

DISNEY, Matthew D., CHILDS-DISNEY, Jessica L.

IPC Classifications

C07D 249/12 20060101AFI20241122BHEP A61P 25/16 20060101ALI20241122BHEP A61P 25/28 20060101ALI20241122BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR