ANTIBODIES BINDING TO CITRULLINATED HISTONE 2A AND/OR 4
Search Report
EP4659807A3
Kind: A3
Mar 18, 2026
Applicants
Citryll B.V.
Inventors
RAATS, Jozef Maria Hendrik, CHIRIVI, Renato Gerardus Silvano, VAN ROSMALEN, Johannes Wilhelmus Gerardus
Abstract
The invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes. The antibodies or binding fragments thereof of the invention can be used in therapy, for example in the treatment or prevention of Neutrophil Extracellular Trap (NET)-associated pathologies.
IPC Classifications
C07K 16/18 20060101AFI20260211BHEP
A61P 29/00 20060101ALI20260211BHEP
A61P 19/02 20060101ALI20260211BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR