← EPO Patent Bulletin

ATTENUATION SYSTEM AND USE THEREOF

Publication EP3795684A1 Kind: A1 Mar 18, 2026

Applicants

CAS Lamvac (Guangzhou) Biomedical Technology Co., Ltd.

Inventors

LIANG, Xingxiang, SU, Jianhua, WANG, Meiling, TONG, Ying, YAO, Yongchao, QIN, Li, CHEN, Xiaoping

Abstract

Disclosed are an attenuation system and the use thereof for attenuating plasmodia, specifically the use of an EF1g gene for attenuating plasmodia. The attenuation system regulates the expression or degradation of the EF1g gene by using a regulatory system, thereby controlling the growth of plasmodia and achieving the attenuation of plasmodia.

IPC Classifications

C12N 15/09 20060101AFI20211130BHEP A61K 39/165 20060101ALI20211130BHEP A61P 33/06 20060101ALI20211130BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR