LACTOBACILLUS PARACASEI STRAIN AND USE THEREOF
Applicants
Kobiolabs, Inc.
Inventors
KO, Gwang Pyo, KIM, Woonki, JANG, You-Jin, SEO, Boram, LEE, June-Chul, NAM, Tae-Wook, KIM, Insu, LEE, Jin- Woo
Abstract
The present invention pertains to: a novel human-derived probiotic strain that is Lactobacillus paracasei KBL382, Lactobacillus paracasei KBL384, or Lactobacillus paracasei KBL385; and a use of the strain for improving intestinal health and treating or preventing intestinal diseases. The strain according to the present invention has excellent anti-inflammatory and immunomodulatory functions, has a superb strengthening effect on tight junctions of the intestinal tract wall, suppresses enteritis-induced weight loss and colon length reduction, thereby exhibiting a therapeutic effect for enteritis, and significantly alleviates the symptoms of atopic dermatitis. Therefore, the strain can be useful as a probiotic material for enhancing anti-inflammatory effects, strengthening immunity, improving intestinal health functions, and alleviating allergic diseases.
IPC Classifications
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR