ANTI-CLDN-5 ANTIBODY, AND DRUG CONTAINING SAID ANTIBODY
Publication
EP3623384A1
Kind: A1
Mar 18, 2026
Applicants
Osaka University
Inventors
KONDOH, Masuo, YAGI, Kiyohito, DOI, Takefumi, OKADA, Yoshiaki, HASHIMOTO, Yosuke, SAWASAKI, Tatsuya, TAKEDA, Hiroyuki, ENDO, Kohki, TAMURA, Maki
Abstract
An object of the present invention is to provide a novel molecule which has high specificity to CLDN-5 and recognizes an extracellular domain of CLDN-5. The object is achieved by an antibody which specifically recognizes a three-dimensional structure or a primary structure of an extracellular domain of a Claudin-5 protein.
IPC Classifications
C07K 16/28 20060101AFI20201222BHEP
A61K 39/395 20060101ALI20201222BHEP
A61K 47/42 20170101ALI20201222BHEP
A61K 47/68 20170101ALI20201222BHEP
A61P 43/00 20060101ALI20201222BHEP
C07K 16/46 20060101ALI20201222BHEP
C12N 1/15 20060101ALI20201222BHEP
C12N 1/19 20060101ALI20201222BHEP
C12N 1/21 20060101ALI20201222BHEP
C12N 5/10 20060101ALI20201222BHEP
C12N 5/12 20060101ALI20201222BHEP
C12N 15/13 20060101ALI20201222BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR